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Last updated: 2017/7/23
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CDH23 polyclonal antibody

  • Catalog # : PAB11508
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of CDH23.
  • Immunogen:
  • A synthetic peptide corresponding to human CDH23.
  • Sequence:
  • C-YNISLYENVTVGTS
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 370, 58.6
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • ELISA (1:1000)
    Western Blot (1-3 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • CDH23 polyclonal antibody (Cat # PAB11508) (1 ug/mL) staining of human amygdala lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • ELISA
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Protein Accession#:
  • NP_071407.4;NP_443068.1
  • Gene Name:
  • CDH23
  • Gene Alias:
  • DFNB12,DKFZp434P2350,FLJ00233,FLJ36499,KIAA1774,KIAA1812,MGC102761,USH1D
  • Gene Description:
  • cadherin-like 23
  • Gene Summary:
  • This gene is a member of the cadherin superfamily, whose genes encode calcium dependent cell-cell adhesion glycoproteins. The encoded protein is a large, single-pass transmembrane protein composed of an extracellular domain containing 27 repeats that show significant homology to the cadherin ectodomain. Expressed in the neurosensory epithelium, the protein is thought to be involved in stereocilia organization and hair bundle formation. The gene is located in a region containing the human deafness loci DFNB12 and USH1D. Usher syndrome 1D and nonsyndromic autosomal recessive deafness DFNB12 are caused by allelic mutations of this cadherin-like gene. Two alternative splice variants have been identified that encode different isoforms. Additional variants have been observed but their full-length nature has not been determined. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000044780,cadherin 23,cadherin related 23,cadherin-23,otocadherin
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