ABCB8 polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of ABCB8.
Immunogen
A synthetic peptide corresponding to human ABCB8.
Sequence
C-KKPEGPRSHQHK
Host
Goat
Theoretical MW (kDa)
78
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:128000)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Enzyme-linked Immunoabsorbent Assay
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Gene Info — ABCB8
Entrez GeneID
11194Protein Accession#
NP_009119.2Gene Name
ABCB8
Gene Alias
EST328128, M-ABC1, MABC1
Gene Description
ATP-binding cassette, sub-family B (MDR/TAP), member 8
Omim ID
605464Gene Ontology
HyperlinkGene Summary
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. The function of this half-transporter has not yet been determined; however, it may involve the compartmentalization and transport of heme, as well as peptides, from the mitochondria to the nucleus and cytosol. This protein may also play a role in the transport of phospholipids into mitochondrial membranes. [provided by RefSeq
Other Designations
ATP-binding cassette, sub-family B, member 8|mitochondrial ABC protein
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Interactome
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Pathway
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Disease
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Publication Reference
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Identification and characterization of a mammalian mitochondrial ATP-binding cassette membrane protein.
Hogue DL, Liu L, Ling V.
Journal of Molecular Biology 1999 Jan; 285(1):379.
Application:IF, WB-Ce, Human, SK-ABC, SKOV3 cells.
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Identification and characterization of a mammalian mitochondrial ATP-binding cassette membrane protein.
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