ABCA12 polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of ABCA12.
Immunogen
A synthetic peptide corresponding to human ABCA12.
Sequence
C-KDQKSYETADTSSQ
Host
Goat
Theoretical MW (kDa)
293, 257
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Enzyme-linked Immunoabsorbent Assay
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Gene Info — ABCA12
Entrez GeneID
26154Protein Accession#
NP_775099.2;NP_056472.2Gene Name
ABCA12
Gene Alias
DKFZp434G232, FLJ41584, ICR2B, LI2
Gene Description
ATP-binding cassette, sub-family A (ABC1), member 12
Gene Ontology
HyperlinkGene Summary
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This encoded protein is a member of the ABC1 subfamily, which is the only major ABC subfamily found exclusively in multicellular eukaryotes. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq
Other Designations
ATP-binding cassette, sub-family A, member 12|ichthyosis congenita II, lamellar ichthyosis B
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Interactome
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Pathway
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Disease
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Publication Reference
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Localization of ABCA12 from Golgi apparatus to lamellar granules in human upper epidermal keratinocytes.
Sakai K, Akiyama M, Sugiyama-Nakagiri Y, McMillan JR, Sawamura D, Shimizu H.
Experimental Dermatology 2007 Nov; 16(11):920.
Application：IEM, IF, IHC-Fr, Human, Human skin biopsies.
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Localization of ABCA12 from Golgi apparatus to lamellar granules in human upper epidermal keratinocytes.
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