ORAI1 polyclonal antibody
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
-
Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of ORAI1.
Immunogen
A synthetic peptide corresponding to human ORAI1.
Sequence
C-KKQPGQPRPTSKP
Host
Goat
Theoretical MW (kDa)
32.7
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:64000)
Western Blot (0.03-0.1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Western Blot (Tissue lysate)
ORAI1 polyclonal antibody (Cat # PAB11461) (0.03 ug/mL) staining of human placenta lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
-
Gene Info — ORAI1
Entrez GeneID
84876Protein Accession#
NP_116179.2Gene Name
ORAI1
Gene Alias
CRACM1, FLJ14466, ORAT1, TMEM142A
Gene Description
ORAI calcium release-activated calcium modulator 1
Omim ID
610277Gene Ontology
HyperlinkGene Summary
CRACM1 is a plasma membrane protein essential for store-operated calcium entry (Vig et al., 2006 [PubMed 16645049]).[supplied by OMIM
Other Designations
calcium release-activated calcium channel protein 1|calcium release-activated calcium modulator 1|transmembrane protein 142A
-
Interactome
-
Publication Reference
-
Defective mast cell effector functions in mice lacking the CRACM1 pore subunit of store-operated calcium release-activated calcium channels.
Vig M, DeHaven WI, Bird GS, Billingsley JM, Wang H, Rao PE, Hutchings AB, Jouvin MH, Putney JW, Kinet JP.
Nature Immunology 2008 Jan; 9(1):89.
-
Mapping the interacting domains of STIM1 and Orai1 in Ca2+ release-activated Ca2+ channel activation.
Li Z, Lu J, Xu P, Xie X, Chen L, Xu T.
The Journal of Biological Chemistry 2007 Oct; 282(40):29448.
-
Defective mast cell effector functions in mice lacking the CRACM1 pore subunit of store-operated calcium release-activated calcium channels.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com