MEIS1 polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of MEIS1.
Immunogen
A synthetic peptide corresponding to human MEIS1.
Sequence
C-SEDITRSANLTDQ
Host
Goat
Theoretical MW (kDa)
43
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:32000)
Western Blot (0.1-0.3 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
MEIS1 polyclonal antibody (Cat # PAB11460) (0.1 ug/mL) staining of human cerebral cortex lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — MEIS1
Entrez GeneID
4211Protein Accession#
NP_002389.1Gene Name
MEIS1
Gene Alias
MGC43380
Gene Description
Meis homeobox 1
Omim ID
601739Gene Ontology
HyperlinkGene Summary
Homeobox genes, of which the most well-characterized category is represented by the HOX genes, play a crucial role in normal development. In addition, several homeoproteins are involved in neoplasia. This gene encodes a homeobox protein belonging to the TALE ('three amino acid loop extension') family of homeodomain-containing proteins. [provided by RefSeq
Other Designations
Meis1, myeloid ecotropic viral integration site 1 homolog|WUGSC:H_NH0444B04.1|leukemogenic homolog protein
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Interactome
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Disease
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Publication Reference
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Meis1 is an essential and rate-limiting regulator of MLL leukemia stem cell potential.
Wong P, Iwasaki M, Somervaille TC, So CW, Cleary ML.
Genes & Development 2007 Nov; 21(21):2762.
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Meis1 is an essential and rate-limiting regulator of MLL leukemia stem cell potential.
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