FTH1 polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
FTH1 polyclonal antibody (Cat # PAB11454) (0.05 ug/mL) staining of human placenta lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of FTH1.
Immunogen
A synthetic peptide corresponding to C-terminus of human FTH1.
Sequence
C-DKHTLGDSDNES
Host
Goat
Theoretical MW (kDa)
21.2
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Recommend Usage
ELISA (1:4000)
Western Blot (0.03-0.1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
FTH1 polyclonal antibody (Cat # PAB11454) (0.05 ug/mL) staining of human placenta lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Immunohistochemistry
Enzyme-linked Immunoabsorbent Assay
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Gene Info — FTH1
Entrez GeneID
2495Protein Accession#
NP_002023.2Gene Name
FTH1
Gene Alias
FHC, FTH, FTHL6, MGC104426, PIG15, PLIF
Gene Description
ferritin, heavy polypeptide 1
Omim ID
134770Gene Ontology
HyperlinkGene Summary
This gene encodes the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative diseases. This gene has multiple pseudogenes. Several alternatively spliced transcript variants have been observed, but their biological validity has not been determined. [provided by RefSeq
Other Designations
apoferritin|placenta immunoregulatory factor|proliferation-inducing protein 15
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Interactome
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Pathway
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Disease
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Publication Reference
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Ferritin L and H subunits are differentially regulated on a post-transcriptional level.
Sammarco MC, Ditch S, Banerjee A, Grabczyk E.
The Journal of Biological Chemistry 2008 Feb; 283(8):4578.
Application：WB, Human, HEK293 cells.
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Ferritin L and H subunits are differentially regulated on a post-transcriptional level.
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