CSRP3 polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
CSRP3 polyclonal antibody (Cat # PAB11452) (0.01 ug/mL) staining of rat heart lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of CSRP3.
Immunogen
A synthetic peptide corresponding to human CSRP3.
Sequence
CGKSLESTNVTDKD
Host
Goat
Theoretical MW (kDa)
21
Reactivity
Human, Mouse, Rat
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:32000)
Western Blot (0.01-0.03 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
CSRP3 polyclonal antibody (Cat # PAB11452) (0.01 ug/mL) staining of rat heart lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — CSRP3
Entrez GeneID
8048Protein Accession#
NP_003467.1Gene Name
CSRP3
Gene Alias
CLP, CMD1M, CMH12, CRP3, LMO4, MGC14488, MGC61993, MLP
Gene Description
cysteine and glycine-rich protein 3 (cardiac LIM protein)
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the CSRP family of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation. The LIM/double zinc-finger motif found in this protein is found in a group of proteins with critical functions in gene regulation, cell growth, and somatic differentiation. Mutations in this gene are thought to cause heritable forms of hypertrophic cardiomyopathy (HCM) and dilated cardiomyopathy (DCM) in humans. Alternatively spliced transcript variants with different 5' UTR, but encoding the same protein, have been found for this gene. [provided by RefSeq
Other Designations
LIM domain only 4|cardiac LIM domain protein|cardiac LIM protein|cysteine and glycine-rich protein 3|cysteine-rich protein 3|muscle LIM protein
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Interactome
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Disease
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Publication Reference
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hhLIM is a novel F-actin binding protein involved in actin cytoskeleton remodeling.
Zheng B, Wen JK, Han M.
FEBS Letters 2008 Apr; 275(7):1568.
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hhLIM is a novel F-actin binding protein involved in actin cytoskeleton remodeling.
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