C1D polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of C1D.
Immunogen
A synthetic peptide corresponding to human C1D.
Sequence
C-SKNASKVANKGKSKS
Host
Goat
Theoretical MW (kDa)
16
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:128000)
Western Blot (0.1-0.3 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
C1D polyclonal antibody (Cat # PAB11451) (0.1 ug/mL) staining of human skeletal muscle lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — C1D
Entrez GeneID
10438Protein Accession#
NP_775269.1Gene Name
C1D
Gene Alias
MGC12261, MGC14659, SUNCOR
Gene Description
nuclear DNA-binding protein
Omim ID
606997Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a DNA binding and apoptosis-inducing protein and is localized in the nucleus. It is also a Rac3-interacting protein which acts as a corepressor for the thyroid hormone receptor. This protein is thought to regulate TRAX/Translin complex formation. Several alternatively spliced transcript variants of this gene have been described, but the full length nature of some of these variants has not been determined. [provided by RefSeq
Other Designations
C1D DNA-binding protein|small unique nuclear receptor corepressor
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Interactome
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Pathway
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Disease
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Publication Reference
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C1D and hMtr4p associate with the human exosome subunit PM/Scl-100 and are involved in pre-rRNA processing.
Schilders G, van Dijk E, Pruijn GJ.
Nucleic Acids Research 2007 Apr; 35(8):2564.
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C1D and hMtr4p associate with the human exosome subunit PM/Scl-100 and are involved in pre-rRNA processing.
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