BTLA polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of BTLA.
Immunogen
A synthetic peptide corresponding to human BTLA.
Sequence
KEAPTEYASICVRS
Host
Goat
Theoretical MW (kDa)
32.8, 27.3
Reactivity
Mouse
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:4000)
Western Blot (1-3 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
BTLA polyclonal antibody (Cat # PAB11450) (1 ug/mL) staining of mouse spleen lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — BTLA
Entrez GeneID
151888Protein Accession#
NP_861445.3;NP_001078826.1Gene Name
BTLA
Gene Alias
BTLA1, CD272, FLJ16065, MGC129743
Gene Description
B and T lymphocyte associated
Omim ID
607925Gene Ontology
HyperlinkGene Summary
BTLA expression is induced during activation of T cells, and BTLA remains expressed on Th1 cells but not Th2 cells. Like PD1 (MIM 600244) and CTLA4 (MIM 123890), BTLA interacts with a B7 homolog, B7H4.[supplied by OMIM
Other Designations
B and T lymphocyte attenuator
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Interactome
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Disease
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Publication Reference
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Targeting of antigen to the herpesvirus entry mediator augments primary adaptive immune responses.
Lasaro MO, Tatsis N, Hensley SE, Whitbeck JC, Lin SW, Rux JJ, Wherry EJ, Cohen GH, Eisenberg RJ, Ertl HC.
Nature Medicine 2008 Feb; 14(2):205.
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Targeting of antigen to the herpesvirus entry mediator augments primary adaptive immune responses.
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