APOL3 polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of APOL3.
Immunogen
A synthetic peptide corresponding to human APOL3.
Sequence
ELTQIYQRLNPCHTH
Host
Goat
Theoretical MW (kDa)
44.3, 36.5, 21.6
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:1000)
Western Blot (1-3 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
APOL3 polyclonal antibody (Cat # PAB11448) (1 ug/mL) staining of Daudi lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — APOL3
Entrez GeneID
80833Protein Accession#
NP_663615.1;NP_055164.1;NP_663616.1Gene Name
APOL3
Gene Alias
APOLIII, CG12-1
Gene Description
apolipoprotein L, 3
Omim ID
607253Gene Ontology
HyperlinkGene Summary
This gene is a member of the apolipoprotein L gene family, and it is present in a cluster with other family members on chromosome 6. The encoded protein is found in the cytoplasm, where it may affect the movement of lipids, including cholesterol, and/or allow the binding of lipids to organelles. In addition, expression of this gene is up-regulated by tumor necrosis factor-alpha in endothelial cells lining the normal and atherosclerotic iliac artery and aorta. Alternative splicing results in multiple transcript variants. [provided by RefSeq
Other Designations
OTTHUMP00000028913|TNF-inducible protein CG12-1|apolipoprotein L-III|apolipoprotein L3
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Interactome
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Disease
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Publication Reference
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The apolipoprotein L gene cluster has emerged recently in evolution and is expressed in human vascular tissue.
Monajemi H, Fontijn RD, Pannekoek H, Horrevoets AJ.
Genomics 2002 Apr; 79(4):539.
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The apolipoprotein L gene cluster has emerged recently in evolution and is expressed in human vascular tissue.
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