APOBEC1 polyclonal antibody
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Specifications
Product Description
Goat polyclonal antibody raised against synthetic peptide of APOBEC1.
Immunogen
A synthetic peptide corresponding to human APOBEC1.
Sequence
DVFYDPRELRKEAC
Host
Goat
Theoretical MW (kDa)
28.2
Reactivity
Mouse
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:32000)
Western Blot (1-3 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
APOBEC1 polyclonal antibody (Cat # PAB11446) (1 ug/mL) staining of mouse spleen lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — APOBEC1
Entrez GeneID
339Protein Accession#
NP_001635.2Gene Name
APOBEC1
Gene Alias
APOBEC-1, BEDP, CDAR1, HEPR
Gene Description
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
Omim ID
600130Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the cytidine deaminase enzyme family. The encoded protein forms a multiple-protein editing holoenzyme with APOBEC1 complementation factor (ACF) and APOBEC1 stimulating protein (ASP). This holoenzyme is involved in the editing of C-to-U nucleotide bases in apolipoprotein B and neurofibromatosis-1 mRNAs. [provided by RefSeq
Other Designations
apolipoprotein B mRNA editing enzyme|apolipoprotein B mRNA editing enzyme complex-1
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Interactomes
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Pathways
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Diseases
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Publication Reference
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Involvement of a chaperone regulator, Bcl2-associated athanogene-4, in apolipoprotein B mRNA editing.
Lau PP, Chan L.
The Journal of Biological Chemistry 2003 Dec; 278(52):52988.
Application:IF, Human, HepG2 cells.
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Involvement of a chaperone regulator, Bcl2-associated athanogene-4, in apolipoprotein B mRNA editing.
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