SEPT7 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
SEPT7 polyclonal antibody (Cat # PAB11439) (0.5 ug/mL) staining of HeLa nuclear extract (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of SEPT7.
Immunogen
A synthetic peptide corresponding to human SEPT7.
Sequence
C-DNNKNKGQLTKSP
Host
Goat
Theoretical MW (kDa)
50.7, 50.6
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:32000)
Western Blot (0.3-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
SEPT7 polyclonal antibody (Cat # PAB11439) (0.5 ug/mL) staining of HeLa nuclear extract (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — SEPT7
Entrez GeneID
989Protein Accession#
NP_001779.3;NP_001011553.2Gene Name
SEPT7
Gene Alias
CDC10, CDC3, Nbla02942, SEPT7A
Gene Description
septin 7
Omim ID
603151Gene Ontology
HyperlinkGene Summary
This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. Although the exact function of this gene has not yet been determined, its high similarity to yeast CDC10 and the high conservative nature of eukaryotic cell cycle machinery suggest a similar role to that of its yeast counterpart. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq
Other Designations
CDC10 (cell division cycle 10, S. cerevisiae, homolog)|CDC10 cell division cycle 10 homolog|cell division cycle 10
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Interactome
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Disease
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Publication Reference
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Septins regulate actin organization and cell-cycle arrest through nuclear accumulation of NCK mediated by SOCS7.
Kremer BE, Adang LA, Macara IG.
Cell 2007 Sep; 130(5):837.
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Septins regulate actin organization and cell-cycle arrest through nuclear accumulation of NCK mediated by SOCS7.
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