ABCE1 polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of ABCE1.
Immunogen
A synthetic peptide corresponding to human ABCE1.
Sequence
NHDKCKPKKCRQEC
Host
Goat
Theoretical MW (kDa)
67.3
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:32000)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Enzyme-linked Immunoabsorbent Assay
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Gene Info — ABCE1
Entrez GeneID
6059Protein Accession#
NP_002931.2;NP_001035809.1Gene Name
ABCE1
Gene Alias
ABC38, OABP, RLI, RNASEL1, RNASELI, RNS4I
Gene Description
ATP-binding cassette, sub-family E (OABP), member 1
Omim ID
601213Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the OABP subfamily. Alternatively referred to as the RNase L inhibitor, this protein functions to block the activity of ribonuclease L. Activation of ribonuclease L leads to inhibition of protein synthesis in the 2-5A/RNase L system, the central pathway for viral interferon action. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
Other Designations
ATP-binding cassette, sub-family E, member 1|RNase L inhibitor|ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) inhibitor
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Interactome
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Disease
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Publication Reference
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ABCE1, a member of ATP-binding cassette transporter gene, encodes peptides capable of inducing HLA-A2-restricted and tumor-reactive cytotoxic T lymphocytes in colon cancer patients.
Shichijo S, Ishihara Y, Azuma K, Komatsu N, Higashimoto N, Ito M, Nakamura T, Ueno T, Harada M, Itoh K.
Oncology Reports 2005 May; 13(5):907.
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ABCE1, a member of ATP-binding cassette transporter gene, encodes peptides capable of inducing HLA-A2-restricted and tumor-reactive cytotoxic T lymphocytes in colon cancer patients.
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