APOBEC3G polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of APOBEC3G.
Immunogen
A synthetic peptide corresponding to human APOBEC3G.
Sequence
C-DEHSQDLSGRLR
Host
Goat
Theoretical MW (kDa)
46.4
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:16000)
Western Blot (0.5-1.5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
APOBEC3G polyclonal antibody (Cat # PAB11417) (0.5 ug/mL) staining of Daudi lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — APOBEC3G
Entrez GeneID
60489Protein Accession#
NP_068594.1Gene Name
APOBEC3G
Gene Alias
ARP9, CEM15, FLJ12740, MDS019, bK150C2.7, dJ494G10.1
Gene Description
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
Omim ID
607113Gene Ontology
HyperlinkGene Summary
This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. The protein encoded by this gene has been found to be a specific inhibitor of human immunodeficiency virus-1 (HIV-1) infectivity. [provided by RefSeq
Other Designations
DNA dC->dU editing enzyme|OTTHUMP00000028911|phorbolin-like protein MDS019
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Interactome
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Pathway
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Disease
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Publication Reference
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Resistance of human T cell leukemia virus type 1 to APOBEC3G restriction is mediated by elements in nucleocapsid.
Derse D, Hill SA, Princler G, Lloyd P, Heidecker G.
PNAS 2007 Feb; 104(8):2915.
Application:WB-Tr, Human, HEK 293T cells.
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Resistance of human T cell leukemia virus type 1 to APOBEC3G restriction is mediated by elements in nucleocapsid.
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