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Last updated: 2016/10/23
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STAT2 (phospho Y690) polyclonal antibody

  • Catalog # : PAB11305
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic phosphopeptide of STAT2.
  • Immunogen:
  • Synthetic phosphopeptide corresponding to residues surrounding Y690 of human STAT2.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Mouse, Rat
  • Specificity:
  • This affinity purified antibody is directed against human STAT2 pY690 protein.
  • Form:
  • Liquid
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • ELISA (1:85000)
    Western Blot (1:500-1:1000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 20 mM KH2PO4, 150 mM NaCl, pH 7.2 (0.01% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot using STAT2 (phospho Y690) polyclonal antibody (Cat # PAB11305) shows detection of STAT2 pY690 protein (arrowhead) in Jurkat cells without (left lane) and with (right lane) 1000 U/mL of IFN-alpha for 15 min at 37°C.
    The primary antibody was used at 1 : 1,000.
    Personal Communication, A.Gamero, NCI, Bethesda, MD.
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 6773
  • Protein Accession#:
  • NP_005410;P52630
  • Gene Name:
  • STAT2
  • Gene Alias:
  • ISGF-3,MGC59816,P113,STAT113
  • Gene Description:
  • signal transducer and activator of transcription 2, 113kDa
  • Gene Summary:
  • The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus. [provided by RefSeq
  • Other Designations:
  • interferon alpha induced transcriptional activator,signal transducer and activator of transcription 2
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