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Last updated: 2016/12/4
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PRKCB polyclonal antibody

  • Catalog # : PAB11251
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of PRKCB.
  • Immunogen:
  • A synthetic peptide corresponding to internal region of human PRKCB.
  • Host:
  • Rabbit
  • Reactivity:
  • Bovine, Human, Monkey, Mouse, Rabbit, Rat
  • Form:
  • Liquid
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • ELISA (1:75000-1:80000)
    Western Blot (1:1000-1:2000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 20 mM KH2PO4, 150 mM NaCl, pH 7.2 (0.01% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot using PRKCB polyclonal antibody (Cat # PAB11251) shows detection of PRKCB in ~25 ug of U251 whole cell lysate (glioma derived).
    The arrowhead corresponds to 76 kDa PRKCB.
    The primary antibody at a 1:1,000 dilution.
    Personal Communication, Howard Fine and Svetlana Kotliarova, CCR-NCI, Bethesda, MD.
  • ELISA
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 5579
  • Protein Accession#:
  • NP_997700.1;P05771
  • Gene Name:
  • PRKCB
  • Gene Alias:
  • MGC41878,PKC-beta,PKCB,PRKCB1,PRKCB2
  • Gene Description:
  • protein kinase C, beta
  • Gene Summary:
  • Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption. Studies in mice also suggest that this kinase may also regulate neuronal functions and correlate fear-induced conflict behavior after stress. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq
  • Other Designations:
  • protein kinase C, beta 1 polypeptide
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