This affinity purified antibody is directed against human PPAR gamma protein. Expect reactivity against human (gamma1 and gamma2), mouse (gamma1 and gamma2), rat, squirrel, orangutan, duck (gamma1), macaque (gamma1-gamma7), boar (gamma1a-1d), mink, guinea pig, rabbit (gamma1 and gamma3), dog and hamster sources based on 100% homology for the immunogen sequence. No reactivity is expected against other subtypes of PPAR.
Quality Control Testing:
Antibody Reactive Against Synthetic Peptide.
ELISA (1:8000-1:32000) The optimal working dilution should be determined by the end user.
In 20 mM KH2PO4, 150 mM NaCl, pH 7.2 (0.01% sodium azide)
Store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing.
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq
OTTHUMP00000185030,OTTHUMP00000185033,OTTHUMP00000185037,PPAR gamma,nuclear receptor subfamily 1 group C member 3,peroxisome proliferative activated receptor gamma,peroxisome proliferative activated receptor, gamma,peroxisome proliferator activated recept