PPP1CA polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
Western blot of PPP1CA polyclonal antibody (Cat # PAB10410) from total rat brain homogenate. (+) indicates staining done in the presence of specific blocking peptide or (-) peptide control.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of PPP1CA.
Immunogen
A synthetic peptide (conjugated with KLH ) corresponding to amino acids 317-330 of PPP1CA.
Sequence
RPITPPRNSAKAKK
Host
Rabbit
Reactivity
Bovine, Human, Mouse, Rat
Form
Liquid
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
Western blot (1:500 to 1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.08% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot of PPP1CA polyclonal antibody (Cat # PAB10410) from total rat brain homogenate. (+) indicates staining done in the presence of specific blocking peptide or (-) peptide control.Immunoprecipitation
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Gene Info — PPP1CA
Entrez GeneID
5499Gene Name
PPP1CA
Gene Alias
MGC15877, MGC1674, PP-1A, PPP1A
Gene Description
protein phosphatase 1, catalytic subunit, alpha isoform
Omim ID
176875Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
protein phosphatase 1, catalytic subunit, alpha|serine/threonine protein phosphatase PP1-alpha 1 catalytic subunit
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Interactome
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Pathway
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