SLC9A1 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot using SLC9A1 polyclonal antibody (Cat # PAB10402) on HT-29 cell lysate. Lysate loaded at 30 ug/lane. Antibody used at 10 ug/mL .
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of SLC9A1.
Immunogen
A synthetic peptide corresponding to human SLC9A1.
Host
Rabbit
Reactivity
Human
Form
Liquid
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
Western blot (1 to 5 mg/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.08% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot using SLC9A1 polyclonal antibody (Cat # PAB10402) on HT-29 cell lysate. Lysate loaded at 30 ug/lane. Antibody used at 10 ug/mL .Western Blot
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Gene Info — SLC9A1
Entrez GeneID
6548Gene Name
SLC9A1
Gene Alias
APNH, FLJ42224, NHE1
Gene Description
solute carrier family 9 (sodium/hydrogen exchanger), member 1
Omim ID
107310Gene Ontology
HyperlinkGene Summary
The Na+/H+ antiporter (SLC9A1) is a ubiquitous membrane-bound enzyme involved in pH regulation of vertebrate cells. It is specifically inhibited by the diuretic drug amiloride and activated by a variety of signals including growth factors, mitogens, neurotransmitters, tumor promoters, and others (Mattei et al., 1988 [PubMed 2846238]).[supplied by OMIM
Other Designations
Na+/H+ antiporter, amiloride-sensitive|Na-Li countertransporter|OTTHUMP00000004468|sodium/hydrogen exchanger 1|solute carrier family 9 (sodium/hydrogen exchanger), isoform 1 (antiporter, Na+/H+, amiloride sensitive)|solute carrier family 9 (sodium/hydroge
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Interactome
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Pathway
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Disease
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Publication Reference
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Structural and functional characterization of transmembrane segment IV of the NHE1 isoform of the Na+/H+ exchanger.
Slepkov ER, Rainey JK, Li X, Liu Y, Cheng FJ, Lindhout DA, Sykes BD, Fliegel L.
The Journal of Biological Chemistry 2005 May; 280(18):17863.
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Proline residues in transmembrane segment IV are critical for activity, expression and targeting of the Na+/H+ exchanger isoform 1.
Slepkov ER, Chow S, Lemieux MJ, Fliegel L.
The Biochemical Journal 2004 Apr; 379(Pt 1):31.
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Expression of calcineurin B homologous protein 2 protects serum deprivation-induced cell death by serum-independent activation of Na+/H+ exchanger.
Pang T, Wakabayashi S, Shigekawa M.
The Journal of Biological Chemistry 2002 Nov; 277(46):43771.
Application：IP, WB-Tr, Human, PS120 cells.
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Structural and functional characterization of transmembrane segment IV of the NHE1 isoform of the Na+/H+ exchanger.
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