SGMS2 polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
Western blot on human brain lysate (10 ug/lane) using SGMS2 polyclonal antibody (Cat # PAB10380) to SGMS2 (0.5 ug/mL).
Lane 1, 1 ug/mL antibody alone.
Lane 2, antibody plus 3 ug blocking peptide.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of SGMS2.
Immunogen
A synthetic peptide corresponding to human SGMS2.
Host
Rabbit
Reactivity
Human
Form
Liquid
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
Western blot (5 to 10 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot (Tissue lysate)
Western blot on human brain lysate (10 ug/lane) using SGMS2 polyclonal antibody (Cat # PAB10380) to SGMS2 (0.5 ug/mL).
Lane 1, 1 ug/mL antibody alone.
Lane 2, antibody plus 3 ug blocking peptide.Enzyme-linked Immunoabsorbent Assay
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Gene Info — SGMS2
Entrez GeneID
166929Gene Name
SGMS2
Gene Alias
MGC26963, SMS2
Gene Description
sphingomyelin synthase 2
Omim ID
611574Gene Ontology
HyperlinkGene Summary
Sphingomyelin, a major component of cell and Golgi membranes, is made by the transfer of phosphocholine from phosphatidylcholine onto ceramide, with diacylglycerol as a side product. The protein encoded by this gene is an enzyme that catalyzes this reaction primarily at the cell membrane. The synthesis is reversible, and this enzyme can catalyze the reaction in either direction. The encoded protein is required for cell growth. Three transcript variants encoding the same protein have been found for this gene. There is evidence for more variants, but the full-length nature of their transcripts has not been determined
Other Designations
OTTHUMP00000162627|OTTHUMP00000162628|SM synthase|phosphatidylcholine:ceramide cholinephosphotransferase 2
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Interactome
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Pathway
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Disease
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Publication Reference
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Identification of a family of animal sphingomyelin synthases.
Huitema K, van den Dikkenberg J, Brouwers JF, Holthuis JC.
The EMBO Journal 2003 Dec; 23(1):33.
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Identification of a family of animal sphingomyelin synthases.
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