RPS6KA1 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of RPS6KA1.
Immunogen
A synthetic peptide corresponding to C-terminus human RPS6KA1.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Specificity
This affinity-purified antibody is directed against the human RSK1 protein.
Form
Liquid
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:2000-1:5000)
Western Blot (1:200-1:1000)
Immunoprecipitation (5 ug/mg per sample)
The optimal working dilution should be determined by the end user.Storage Buffer
In 100 mM Tris-Cl, 500 mM NaCl, pH 8.0 (0.01% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of RPS6KA1 immunoprecipitated from the mouse brain extract (lane 2) and using RPS6KA1-HRP as a probe. Immunoprecipitated negative control (lane 1).Immunofluorescence
Enzyme-linked Immunoabsorbent Assay
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Gene Info — RPS6KA1
Entrez GeneID
6195Protein Accession#
Q15418;NP_002944Gene Name
RPS6KA1
Gene Alias
HU-1, MAPKAPK1A, RSK, RSK1
Gene Description
ribosomal protein S6 kinase, 90kDa, polypeptide 1
Omim ID
601684Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq
Other Designations
OTTHUMP00000004113|S6K-alpha 1|dJ590P13.1 (ribosomal protein S6 kinase, 90kD, polypeptide 1)|p90-RSK 1|ribosomal protein S6 kinase alpha 1|ribosomal protein S6 kinase, 90kD, 1|ribosomal protein S6 kinase, 90kD, polypeptide 1
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Interactome
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Disease
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