Western blot using IRAK1 polyclonal antibody (Cat # PAB10249) shows detection of IRAK1 in THP-1 whole cell lysate (THP) or HeLa whole cell lysate (HL). The membrane was probed with the primary antibody diluted to 1 : 2,000.
Immunocytochemistry using IRAK1 polyclonal antibody (Cat # PAB10249) shows staining of IRAK1 in HeLa cells. The cells were fixed with paraformaldehyde and reacted with the primary antibody diluted to 1 : 100.
This gene encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. This gene is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq