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Last updated: 2016/10/23
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FBXW11 polyclonal antibody

  • Catalog # : PAB10237
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of FBXW11.
  • Immunogen:
  • A synthetic peptide corresponding to N-terminus of human FBXW11.
  • Host:
  • Rabbit
  • Reactivity:
  • Bovine, Chicken, Chimpanzee, Dog, Horse, Human, Mouse
  • Specificity:
  • This antibody reacts with human betaTrCP2 protein.
  • Form:
  • Liquid
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • ELISA (1:10000-1:100000)
    Western Blot (1:200-1:1000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 20 mM KH2PO4, 150 mM NaCl, pH 7.2 (0.01% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot using FBXW11 polyclonal antibody (Cat # PAB10237) shows detection of mouse and human FBXW11 (arrowhead) in NIH/3T3 (Lane 1) and 293 (Lane 2) whole cell lysates, respectively.
    The band appears as a 58 KDa protein, although a 62.1 KDa band is predicted.
    The identity of faint higher molecular weight bands is not known.
    The primary antibody was used at a 1 : 200 dilution incubated in 5% BLOTTO overnight at 4°C.
    Detection occurred using HRP conjugated Goat-anti-Rabbit IgG diluted 1 : 20,000 in blocking buffer for 1 h at 4°C.
  • Immunofluorescence
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunofluorescence
  • Gene Information
  • Protein Accession#:
  • NP_387449;Q9UKB1
  • Gene Name:
  • FBXW11
  • Gene Alias:
  • BTRC2,BTRCP2,FBW1B,FBXW1B,Fbw11,Hos,KIAA0696
  • Gene Description:
  • F-box and WD repeat domain containing 11
  • Gene Summary:
  • This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class and, in addition to an F-box, contains multiple WD40 repeats. This gene contains at least 14 exons, and its alternative splicing generates 3 transcript variants diverging at the presence/absence of two alternate exons. [provided by RefSeq
  • Other Designations:
  • F-box and WD-40 domain protein 11,F-box and WD-40 domain protein 1B,F-box protein Fbw1b,beta-transducin repeat-containing protein 2
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