FN1 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against native FN1.
Immunogen
Native purified FN1 from human plasma.
Host
Rabbit
Reactivity
Human
Specificity
This antibody reacts with human Fibronectin and has negligible cross-reactivity with Type I, II, III, IV, V or VI collagens or Laminin. Non-specific cross reaction of anti-Fibronectin antibodies with other human serum proteins or non-Fibronectin extracellular matrix proteins is negligible.
Form
Liquid
Quality Control Testing
Antibody Reactive Against Native Purified Protein.
Recommend Usage
ELISA (1:5000-1:10000)
Western Blot (1:5000-1:10000)
Immunohistochemistry (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In 20 mM KH2PO4, 150 mM NaCl, pH 7.2 (0.01% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Immunohistochemistry
Immunoprecipitation
Enzyme-linked Immunoabsorbent Assay
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Gene Info — FN1
Entrez GeneID
2335Gene Name
FN1
Gene Alias
CIG, DKFZp686F10164, DKFZp686H0342, DKFZp686I1370, DKFZp686O13149, ED-B, FINC, FN, FNZ, GFND, GFND2, LETS, MSF
Gene Description
fibronectin 1
Omim ID
135600Gene Ontology
HyperlinkGene Summary
This gene encodes fibronectin, a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. Fibronectin is involved in cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. The gene has three regions subject to alternative splicing, with the potential to produce 20 different transcript variants. However, the full-length nature of some variants has not been determined. [provided by RefSeq
Other Designations
cold-insoluble globulin|migration-stimulating factor
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Interactome
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Pathway
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Disease
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Publication Reference
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Cell surface interactions with extracellular materials.
Yamada KM.
Annual Review of Biochemistry 1983 Jan; 52:761.
Application:ELISA, IA, IEM, IF, Human, Human hepatocytes, Human plasma.
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Cell surface interactions with extracellular materials.
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