ODF2 polyclonal antibody
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of ODF2.
Immunogen
A synthetic peptide corresponding to C-terminus of human ODF2.
Host
Rabbit
Reactivity
Chimpanzee, Human, Macaque
Specificity
This antibody is specific to human Cenexin-1 protein.
Form
Liquid
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:2000-1:10000)
Western Blot (1:200-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In 20 mM KH2PO4, 150 mM NaCl, pH 7.2 (0.01% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Immunohistochemistry
Enzyme-linked Immunoabsorbent Assay
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Gene Info — ODF2
Entrez GeneID
4957Protein Accession#
ABE01857;Q6UN26Gene Name
ODF2
Gene Alias
FLJ44866, MGC111096, MGC9034, ODF2/1, ODF2/2, ODF84
Gene Description
outer dense fiber of sperm tails 2
Omim ID
602015Gene Ontology
HyperlinkGene Summary
The outer dense fibers are cytoskeletal structures that surround the axoneme in the middle piece and principal piece of the sperm tail. The fibers function in maintaining the elastic structure and recoil of the sperm tail as well as in protecting the tail from shear forces during epididymal transport and ejaculation. Defects in the outer dense fibers lead to abnormal sperm morphology and infertility. This gene encodes one of the major outer dense fiber proteins. Multiple protein isoforms are encoded by transcript variants of this gene; however, not all isoforms and variants have been fully described. [provided by RefSeq
Other Designations
OTTHUMP00000022273|OTTHUMP00000022274|cenexin 1|outer dense fiber of sperm tails, 84-kD|outer dense fibre of sperm tails 2|sperm tail structural protein
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Interactome
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Disease
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Publication Reference
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Requirement of hCenexin for proper mitotic functions of polo-like kinase 1 at the centrosomes.
Soung NK, Kang YH, Kim K, Kamijo K, Yoon H, Seong YS, Kuo YL, Miki T, Kim SR, Kuriyama R, Giam CZ, Ahn CH, Lee KS.
Molecular and Cellular Biology 2006 Nov; 26(22):8316.
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Keratins: unraveling the coordinated construction of scaffolds in spermatogenic cells.
Kierszenbaum AL.
Molecular Reproduction and Development 2002 Jan; 61(1):1.
Application：WB, Human, Spermatogenic cells.
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Outer dense fibre proteins from human sperm tail: molecular cloning and expression analyses of two cDNA transcripts encoding proteins of approximately 70 kDa.
Petersen C, Füzesi L, Hoyer-Fender S.
Molecular Human Reproduction 1999 Jul; 5(7):627.
Application：ICC, WB-Ce, Human, Mouse, Rat, Spermatozoa.
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Requirement of hCenexin for proper mitotic functions of polo-like kinase 1 at the centrosomes.
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