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Last updated: 2016/12/4
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NUMB polyclonal antibody

  • Catalog # : PAB10143
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of NUMB.
  • Immunogen:
  • A synthetic peptide corresponding to human NUMB.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • Western blot (1 to 5 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.08% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • 1.
  • Siah-1 binds and regulates the function of Numb.
    Susini L, Passer BJ, Amzallag-Elbaz N, Juven-Gershon T, Prieur S, Privat N, Tuynder M, Gendron MC, Israel A, Amson R, Oren M, Telerman A.Proc Natl Acad Sci U S A. 2001 Dec 18;98(26):15067-72.
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • Western blot using NUMB polyclonal antibody (Cat # PAB10143) on human brain lysate. Lysate used at 14 ug/lane. Antibody used at 10 ug/mL .
  • Western Blot
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 8650
  • Gene Name:
  • NUMB
  • Gene Alias:
  • S171
  • Gene Description:
  • numb homolog (Drosophila)
  • Gene Summary:
  • The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • numb homolog
  • Interactome
  • Interactome
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