NTN1 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot using NTN1 polyclonal antibody (Cat # PAB10137) at 5 ug/mL on MDCK II cell extract (10 ug/lane).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of NTN1.
Immunogen
A synthetic peptide corresponding to human NTN1.
Host
Rabbit
Reactivity
Bovine, Cat, Human, Macaque, Mouse, Rat
Form
Liquid
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
Western blot (0.5 to 2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.08% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot using NTN1 polyclonal antibody (Cat # PAB10137) at 5 ug/mL on MDCK II cell extract (10 ug/lane).Western Blot
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Gene Info — NTN1
Entrez GeneID
9423Gene Name
NTN1
Gene Alias
NTN1L
Gene Description
netrin 1
Omim ID
601614Gene Ontology
HyperlinkGene Summary
Netrin is included in a family of laminin-related secreted proteins. The function of this gene has not yet been defined; however, netrin is thought to be involved in axon guidance and cell migration during development. Mutations and loss of expression of netrin suggest that variation in netrin may be involved in cancer development. [provided by RefSeq
Other Designations
Netrin-1|netrin 1, mouse, homolog of
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Interactome
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Pathway
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Publication Reference
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Netrin-1 induces angiogenesis via a DCC-dependent ERK1/2-eNOS feed-forward mechanism.
Nguyen A, Cai H.
PNAS 2006 Apr; 103(17):6530.
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Deleted in colorectal cancer binding netrin-1 mediates cell substrate adhesion and recruits Cdc42, Rac1, Pak1, and N-WASP into an intracellular signaling complex that promotes growth cone expansion.
Shekarabi M, Moore SW, Tritsch NX, Morris SJ, Bouchard JF, Kennedy TE.
The Journal of Neuroscience 2005 Mar; 25(12):3132.
Application：Incubation, Recombinant protein.
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Netrin-1 is a chemorepellent for oligodendrocyte precursor cells in the embryonic spinal cord.
Jarjour AA, Manitt C, Moore SW, Thompson KM, Yuh SJ, Kennedy TE.
Journal of Neuroscience 2003 May; 23(9):3735.
Application：IF, Rat, Rat oligodendrocyte precursor cell culture.
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Netrin-1 induces angiogenesis via a DCC-dependent ERK1/2-eNOS feed-forward mechanism.
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