SLC16A8 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of SLC16A8.
Immunogen
A synthetic peptide corresponding to SLC16A8.
Host
Rabbit
Reactivity
Human
Form
Liquid
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
Western blot (1 to 5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.08% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis using SLC16A8 polyclonal antibody (Cat # PAB10133) on human brain lysate. Lysate loaded at 15 ug/lane. Antibody used at 5 ug/mL .Western Blot
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Gene Info — SLC16A8
Entrez GeneID
23539Gene Name
SLC16A8
Gene Alias
MCT3, REMP
Gene Description
solute carrier family 16, member 8 (monocarboxylic acid transporter 3)
Omim ID
610409Gene Ontology
HyperlinkGene Summary
Lactate transport across cell membranes is mediated by proton-coupled monocarboxylate transporters, such as SLC16A8 Yoon et al. (1999) [PubMed 10493836].[supplied by OMIM
Other Designations
OTTHUMP00000028510|monocarboxylate transporter 3|solute carrier 16 (monocarboxylic acid transporters), member 8|solute carrier family 16, member 8
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Interactome
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Disease
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Publication Reference
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Inactivation of monocarboxylate transporter MCT3 by DNA methylation in atherosclerosis.
Zhu S, Goldschmidt-Clermont PJ, Dong C.
Circulation 2005 Aug; 112(9):1353.
Application:IHC-P, WB-Ce, WB-Tr, Human, Cardiac, Aortic SMCs.
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Loss of MCT1, MCT3, and MCT4 expression in the retinal pigment epithelium and neural retina of the 5A11/basigin-null mouse.
Philp NJ, Ochrietor JD, Rudoy C, Muramatsu T, Linser PJ.
Investigative Ophthalmology & Visual Science 2003 Mar; 44(3):1305.
Application:IF, IHC, WB, Mouse, Mouse retina.
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Cloning of the human monocarboxylate transporter MCT3 gene: localization to chromosome 22q12.3-q13.2.
Yoon H, Donoso LA, Philp NJ.
Genomics 1999 Sep; 60(3):366.
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Inactivation of monocarboxylate transporter MCT3 by DNA methylation in atherosclerosis.
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