LPAR3 polyclonal antibody
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of LPAR3.
Immunogen
A synthetic peptide corresponding to C-terminus of human LPAR3.
Host
Rabbit
Reactivity
Human
Form
Liquid
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In PBS (0.08% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western blot analysis using LPAR3 polyclonal antibody (Cat # PAB10127) on McA-RH7777 cell lysates transfected with full length human LPAR3. -
Gene Info — LPAR3
Entrez GeneID
23566Gene Name
LPAR3
Gene Alias
EDG7, Edg-7, FLJ98231, GPCR, HOFNH30, LP-A3, LPA3, RP4-678I3
Gene Description
lysophosphatidic acid receptor 3
Omim ID
605106Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the G protein-coupled receptor family, as well as the EDG family of proteins. This protein functions as a cellular receptor for lysophosphatidic acid and mediates lysophosphatidic acid-evoked calcium mobilization. This receptor couples predominantly to G(q/11) alpha proteins. [provided by RefSeq
Other Designations
LPA receptor EDG7|OTTHUMP00000011573|calcium-mobilizing lysophosphatidic acid receptor LP-A3|endothelial cell differentiation gene 7|endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 7
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Interactome
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Pathway
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Disease
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Publication Reference
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Molecular cloning and characterization of a lysophosphatidic acid receptor, Edg-7, expressed in prostate.
Im DS, Heise CE, Harding MA, George SR, O'Dowd BF, Theodorescu D, Lynch KR.
Molecular Pharmacology 2000 Apr; 57(4):753.
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Lysophospholipid growth factors in the initiation, progression, metastases, and management of ovarian cancer.
Fang X, Gaudette D, Furui T, Mao M, Estrella V, Eder A, Pustilnik T, Sasagawa T, Lapushin R, Yu S, Jaffe RB, Wiener JR, Erickson JR, Mills GB.
Annals of the New York Academy of Sciences 2000 Apr; 905:188.
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Molecular cloning and characterization of a novel human G-protein-coupled receptor, EDG7, for lysophosphatidic acid.
Bandoh K, Aoki J, Hosono H, Kobayashi S, Kobayashi T, Murakami-Murofushi K, Tsujimoto M, Arai H, Inoue K.
The Journal of Biological Chemistry 1999 Sep; 274(39):27776.
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Molecular cloning and characterization of a lysophosphatidic acid receptor, Edg-7, expressed in prostate.
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