LASS6 polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
Western blot analysis using LASS6 polyclonal antibody (Cat # PAB10112) at 6 ug/mL on human duodenum lysate 14 ug/lane. Lane 1, antibody alone. Lane 2, antibody plus 50 ug blocking peptide.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of LASS6.
Immunogen
A synthetic peptide of human LASS6.
Host
Rabbit
Reactivity
Human
Form
Liquid
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
Western blot (5 to 7 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.08% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis using LASS6 polyclonal antibody (Cat # PAB10112) at 6 ug/mL on human duodenum lysate 14 ug/lane. Lane 1, antibody alone. Lane 2, antibody plus 50 ug blocking peptide. -
Gene Info — LASS6
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Interactome
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Disease
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Publication Reference
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Inactivation of ceramide synthase 6 in mice results in an altered sphingolipid metabolism and behavioral abnormalities.
Ebel P, Vom Dorp K, Petrasch-Parwez E, Zlomuzica A, Kinugawa K, Mariani J, Minich D, Ginkel C, Welcker J, Degen J, Eckhardt M, Dere E, Dormann P, Willecke K.
The Journal of Biological Chemistry 2013 Jul; 288(29):21433.
Application：WB-Ce, WB-Ti, Human, Mouse, HEK 293, Thymus, Small intestine, Large intestine, Kidney, Forebrain, Cerebellum.
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LASS3 (longevity assurance homologue 3) is a mainly testis-specific (dihydro)ceramide synthase with relatively broad substrate specificity.
Mizutani Y, Kihara A, Igarashi Y.
The Biochemical Journal 2006 Sep; 398(3):531.
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The CLN9 protein, a regulator of dihydroceramide synthase.
Schulz A, Mousallem T, Venkataramani M, Persaud-Sawin DA, Zucker A, Luberto C, Bielawska A, Bielawski J, Holthuis JC, Jazwinski SM, Kozhaya L, Dbaibo GS, Boustany RM.
The Journal of Biological Chemistry 2006 Feb; 281(5):2784.
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LASS6, an additional member of the longevity assurance gene family.
Weinmann A, Galle PR, Teufel A.
International Journal of Molecular Medicine 2005 Nov; 16(5):905.
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Inactivation of ceramide synthase 6 in mice results in an altered sphingolipid metabolism and behavioral abnormalities.
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