IBTK polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of IBTK.
Immunogen
A synthetic peptide corresponding to amino acids 1205-1217 of human IBTK.
Host
Rabbit
Reactivity
Human
Form
Liquid
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:15000-1:65000)
The optimal working dilution should be determined by the end user.Storage Buffer
In 20 mM KH2PO4, 150 mM NaCl, pH 7.2 (0.01% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Enzyme-linked Immunoabsorbent Assay
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Gene Info — IBTK
Entrez GeneID
25998Gene Name
IBTK
Gene Alias
BTKI, KIAA1417, MGC142256, MGC142258, RP1-93K22.1
Gene Description
inhibitor of Bruton agammaglobulinemia tyrosine kinase
Omim ID
606457Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene binds to Bruton's tyrosine kinase (BTK) and downregulates BTK's kinase activity. In addition, the encoded protein disrupts BTK-mediated calcium mobilization and negatively regulates the activation of nuclear factor-kappa-B-driven transcription. [provided by RefSeq
Other Designations
BTK-binding protein|Bruton agammaglobulinemia tyrosine kinase inhibitor|OTTHUMP00000040002|inhibitor of Bruton's tyrosine kinase|inhibitor of Bruton's tyrosine kinase-alpha|inhibitor of Bruton's tyrosine kinase-beta|inhibitor of Bruton's tyrosine kinase-g
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