APC2 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of APC2.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to amino acids 810-822 of human APC2.
Host
Rabbit
Reactivity
Human
Specificity
Cross reactivity may also occur with APC2 from other sources. Sufficient sequence differences exist to suggest that this antibody would not react with other RING box proteins such as ROC1 and ROC2.
Form
Liquid
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:2000-1:10000)
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In antiserum (0.01% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Immunohistochemistry
Enzyme-linked Immunoabsorbent Assay
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Gene Info — APC2
Entrez GeneID
10297Protein Accession#
NP_037498;Q9UJX6Gene Name
APC2
Gene Alias
APCL
Gene Description
adenomatosis polyposis coli 2
Gene Ontology
HyperlinkOther Designations
adenomatous polyposis coli like
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Interactome
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Pathway
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Disease
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Publication Reference
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Ubiquitin and its kin: how close are the family ties?
Jentsch S, Pyrowolakis G.
Trends in Cell Biology 2000 Aug; 10(8):335.
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Identification of a cullin homology region in a subunit of the anaphase-promoting complex.
Yu H, Peters JM, King RW, Page AM, Hieter P, Kirschner MW.
Science 1998 Feb; 279(5354):1219.
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Mass spectrometric analysis of the anaphase-promoting complex from yeast: identification of a subunit related to cullins.
Zachariae W, Shevchenko A, Andrews PD, Ciosk R, Galova M, Stark MJ, Mann M, Nasmyth K.
Science 1998 Feb; 279(5354):1216.
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Ubiquitin and its kin: how close are the family ties?
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