SPA17 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against a synthetic peptide of SPA17.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human SPA17.
Host
Rabbit
Reactivity
Human
Form
Liquid
Recommend Usage
Western Blot (1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.2% gelatin, 0.09% sodium azide)
Storage Instruction
Store at 4°C. Do not freeze.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
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Gene Info — SPA17
Entrez GeneID
53340Gene Name
SPA17
Gene Alias
SP17, SP17-1
Gene Description
sperm autoantigenic protein 17
Omim ID
608621Gene Ontology
HyperlinkGene Summary
This gene encodes a protein present at the cell surface. The N-terminus has sequence similarity to human cAMP-dependent protein kinase A (PKA) type II alpha regulatory subunit (RIIa) while the C-terminus has an IQ calmodulin-binding motif. The central portion of the protein has carbohydrate binding motifs and likely functions in cell-cell adhesion. The protein was initially characterized by its involvement in the binding of sperm to the zona pellucida of the oocyte. Recent studies indicate that it is also involved in additional cell-cell adhesion functions such as immune cell migration and metastasis. A retrotransposed pseudogene is present on chromosome 10q22
Other Designations
sperm protein 17
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