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SPA17 polyclonal antibody

  • Catalog # : PAB0869
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against a synthetic peptide of SPA17.
  • Immunogen:
  • A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human SPA17.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Recommend Usage:
  • Western Blot (1:200)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.2% gelatin, 0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. Do not freeze.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Application Image
  • Western Blot (Cell lysate)
  • Gene Information
  • Gene Name:
  • SPA17
  • Gene Alias:
  • SP17,SP17-1
  • Gene Description:
  • sperm autoantigenic protein 17
  • Gene Summary:
  • This gene encodes a protein present at the cell surface. The N-terminus has sequence similarity to human cAMP-dependent protein kinase A (PKA) type II alpha regulatory subunit (RIIa) while the C-terminus has an IQ calmodulin-binding motif. The central portion of the protein has carbohydrate binding motifs and likely functions in cell-cell adhesion. The protein was initially characterized by its involvement in the binding of sperm to the zona pellucida of the oocyte. Recent studies indicate that it is also involved in additional cell-cell adhesion functions such as immune cell migration and metastasis. A retrotransposed pseudogene is present on chromosome 10q22
  • Other Designations:
  • sperm protein 17
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