CBL polyclonal antibody
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More Files
- More Functions
Western Blot
Western blot of human CBL polyclonal antibody (Cat # PAB0864) expression in Jurkat (A) and K-562 (B) whole cell lysates.
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Specification
Product Description
Rabbit polyclonal antibody raised against a synthetic peptide of CBL.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human CBL.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Recommend Usage
Western Blot (1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.2% gelatin, 0.09% sodium azide)
Storage Instruction
Store at 4°C. Do not freeze.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot of human CBL polyclonal antibody (Cat # PAB0864) expression in Jurkat (A) and K-562 (B) whole cell lysates. -
Gene Info — CBL
Entrez GeneID
867Gene Name
CBL
Gene Alias
C-CBL, CBL2, RNF55
Gene Description
Cas-Br-M (murine) ecotropic retroviral transforming sequence
Omim ID
165360Gene Ontology
HyperlinkGene Summary
The cbl oncogene was first identified as part of a transforming retrovirus which induces mouse pre-B and pro-B cell lymphomas. As an adaptor protein for receptor protein-tyrosine kinases, it positively regulates receptor protein-tyrosine kinase ubiquitination in a manner dependent upon its variant SH2 and RING finger domains. Ubiquitination of receptor protein-tyrosine kinases terminates signaling by marking active receptors for degradation. [provided by RefSeq
Other Designations
oncogene CBL2
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Interactome
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Pathway
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Disease
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