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Last updated: 2017/7/23
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RBL1 polyclonal antibody

  • Catalog # : PAB0849
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against a synthetic peptide of RBL1.
  • Immunogen:
  • A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human RBL1.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Mouse, Rat
  • Form:
  • Liquid
  • Recommend Usage:
  • Western Blot (1:200)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.2% gelatin, 0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. Do not freeze.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Application Image
  • Western Blot (Cell lysate)
  • Gene Information
  • Entrez GeneID:
  • 5933
  • Gene Name:
  • RBL1
  • Gene Alias:
  • CP107,MGC40006,PRB1,p107
  • Gene Description:
  • retinoblastoma-like 1 (p107)
  • Gene Summary:
  • The protein encoded by this gene is similar in sequence and possibly function to the product of the retinoblastoma 1 (RB1) gene. The RB1 gene product is a tumor suppressor protein that appears to be involved in cell cycle regulation, as it is phosphorylated in the S to M phase transition and is dephosphorylated in the G1 phase of the cell cycle. Both the RB1 protein and the product of this gene can form a complex with adenovirus E1A protein and SV40 large T-antigen, with the SV40 large T-antigen binding only to the unphosphorylated form of each protein. In addition, both proteins can inhibit the transcription of cell cycle genes containing E2F binding sites in their promoters. Due to the sequence and biochemical similarities with the RB1 protein, it is thought that the protein encoded by this gene may also be a tumor suppressor. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • 107 kDa retinoblastoma-associated protein,OTTHUMP00000030892,OTTHUMP00000030893,cellular protein 107,retinoblastoma-like protein 1
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  • Interactome
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