BCL2L1 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against a synthetic peptide of BCL2L1.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human BCL2L1.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In PBS (0.2% gelatin, 0.09% sodium azide)
Storage Instruction
Store at 4°C. Do not freeze.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot detection against Immunogen. -
Gene Info — BCL2L1
Entrez GeneID
598Gene Name
BCL2L1
Gene Alias
BCL-XL/S, BCL2L, BCLX, Bcl-X, DKFZp781P2092, bcl-xL, bcl-xS
Gene Description
BCL2-like 1
Omim ID
600039Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported. The longer isoform acts as an apoptotic inhibitor and the shorter form acts as an apoptotic activator. [provided by RefSeq
Other Designations
OTTHUMP00000030550|OTTHUMP00000030551|OTTHUMP00000030553
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Interactome
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Pathway
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Disease
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Publication Reference
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CpG-oligodeoxynucleotide protects immune cells from gamma-irradiation-induced cell death.
Sohn WJ, Lee KW, Choi SY, Chung E, Lee Y, Kim TY, Lee SK, Choe YK, Lee JH, Kim DS, Kwon HJ.
Molecular Immunology 2005 Aug; 43(8):1163.
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CpG-oligodeoxynucleotide protects immune cells from gamma-irradiation-induced cell death.
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