AUP1 polyclonal antibody
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Specification
Product Description
Sheep polyclonal antibody raised against synthetic peptide of AUP1.
Immunogen
A synthetic peptide (conjugated with Blue Carrier Protein) corresponding to amino acids 48-60 of human AUP1.
Sequence
HVFLVSCALPDSV
Host
Sheep
Reactivity
Bovine, Human, Rat, Sheep
Specificity
This antiserum is specific to ancient ubiquitous protein 1.
Form
Lyophilized
Recommend Usage
Immunohistochemistry (1:500-1:6000)
Western Blot (1:500-1:6000)
The optimal dilution should be determined by the end user.Storage Buffer
Lyophilized from PBS
Storage Instruction
Store at 4°C on dry atmosphere.
After reconstitution with deionized water, store at -20°C or lower.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot
Immunohistochemistry (Frozen sections)
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Gene Info — AUP1
Entrez GeneID
550Protein Accession#
Q9Y679;Q3ZC65;P70295;A1L134Gene Name
AUP1
Gene Alias
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Gene Description
ancient ubiquitous protein 1
Omim ID
602434Gene Ontology
HyperlinkGene Summary
This gene encodes a protein that contains a domain with homology to the ancient conserved region of the archain 1 gene and a domain that may be involved in binding ubiquitin-conjugating enzymes. The protein encoded by this gene has been shown to bind to the conserved membrane-proximal sequence of the cytoplasmic tail of integrin alpha(IIb) subunits. These subunits play a crucial role in the integrin alpha(IIb)beta(3) inside-out signalling in platelets and megakaryocytes that leads to platelet aggregation and thrombus formation. This gene overlaps the gene for mitochondrial serine protease 25. [provided by RefSeq
Other Designations
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Interactome
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