BDNF polyclonal antibody
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Specification
Product Description
Sheep polyclonal antibody raised against full length recombinant BDNF.
Immunogen
Recombinant protein corresponding to full length human BDNF.
Host
Sheep
Reactivity
Human, Rat
Specificity
A cross reactivity of less than 1% against mouse NGF, recombinant human NT3 or NT4/5 has been shown by one site ELISA.
Form
Lyophilized
Purification
Protein G purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1-10 ug/mL)
ELISA (1-10 ug/mL)
Western Blot (1-10 ug/mL)
Inhibition assay (1-10 ug/mL in vitro 2-10 ug/mL (ED50) in vivo)
The optimal working dilution should be determined by the end user.Storage Buffer
Lyophilized from PBS
Storage Instruction
Store at -20°C.
After reconstitution with deionized water, store at -20°C or lower.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot
Immunohistochemistry (Frozen sections)
Enzyme-linked Immunoabsorbent Assay
Inhibition Assay
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Gene Info — BDNF
Entrez GeneID
627Protein Accession#
P23560Gene Name
BDNF
Gene Alias
MGC34632
Gene Description
brain-derived neurotrophic factor
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the nerve growth factor family. It is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. Expression of this gene is reduced in both Alzheimer's and Huntington disease patients. This gene may play a role in the regulation of stress response and in the biology of mood disorders. Multiple transcript variants encoding distinct isoforms have been described for this gene. [provided by RefSeq
Other Designations
neurotrophin
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Interactome
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Pathway
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Disease
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