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Last updated: 2016/12/4
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BDNF polyclonal antibody

  • Catalog # : PAB0747
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  • Specification
  • Product Description:
  • Sheep polyclonal antibody raised against full length recombinant BDNF.
  • Immunogen:
  • Recombinant protein corresponding to full length human BDNF.
  • Host:
  • Sheep
  • Reactivity:
  • Human, Rat
  • Specificity:
  • A cross reactivity of less than 1% against mouse NGF, recombinant human NT3 or NT4/5 has been shown by one site ELISA.
  • Form:
  • Lyophilized
  • Purification:
  • Protein G purification
  • Isotype:
  • IgG
  • Recommend Usage:
  • Immunohistochemistry (1-10 ug/mL)
    ELISA (1-10 ug/mL)
    Western Blot (1-10 ug/mL)
    Inhibition assay (1-10 ug/mL in vitro 2-10 ug/mL (ED50) in vivo)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • Lyophilized from PBS
  • Storage Instruction:
  • Store at -20°C.
    After reconstitution with deionized water, store at -20°C or lower.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Immunohistochemistry (Frozen sections)
  • ELISA
  • Inhibition Assay
  • Application Image
  • Western Blot
  • Immunohistochemistry (Frozen sections)
  • ELISA
  • Inhibition Assay
  • Gene Information
  • Entrez GeneID:
  • 627
  • Gene Name:
  • BDNF
  • Gene Alias:
  • MGC34632
  • Gene Description:
  • brain-derived neurotrophic factor
  • Gene Summary:
  • The protein encoded by this gene is a member of the nerve growth factor family. It is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. Expression of this gene is reduced in both Alzheimer's and Huntington disease patients. This gene may play a role in the regulation of stress response and in the biology of mood disorders. Multiple transcript variants encoding distinct isoforms have been described for this gene. [provided by RefSeq
  • Other Designations:
  • neurotrophin
  • Related Disease
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