ATG4B polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of ATG4B.
Immunogen
A synthetic peptide (conjugated with Blue Carrier Protein) corresponding to N-terminus of human ATG4B.
Host
Rabbit
Reactivity
Human, Rat
Form
Lyophilized
Recommend Usage
Immunohistochemistry (1:100-1:2000)
Immunofluorescence (1:100-1:2000)
Western Blot (1:100-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
Lyophilized from PBS
Storage Instruction
Store at 4°C on dry atmosphere.
After reconstitution with deionized water, store at -20°C or lower.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot (Cell lysate)
Western blot on 293 cell lysate using rabbit ATG4B polyclonal antibody (Cat # PAB0738) at a dilution of 1 : 100.Immunohistochemistry (Frozen sections)
Immunofluorescence
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Gene Info — ATG4B
Entrez GeneID
23192Protein Accession#
Q9Y4P1;Q8BGE6;71043632Gene Name
ATG4B
Gene Alias
APG4B, AUTL1, MGC1353
Gene Description
ATG4 autophagy related 4 homolog B (S. cerevisiae)
Omim ID
611338Gene Ontology
HyperlinkGene Summary
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq
Other Designations
APG4 autophagy 4 homolog B|autophagin-1
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Interactome
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