NTRK3 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant NTRK3.
Immunogen
Recombinant protein corresponding to extracellular region of human NTRK3.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Lyophilized
Recommend Usage
Immunohistochemistry (1:1000-1:3000)
The optimal working dilution should be determined by the end user.Storage Buffer
Lyophilized from PBS
Storage Instruction
Store at 4°C on dry atmosphere.
After reconstitution with deionized water, store at -20°C or lower.
Aliquot to avoid repeated freezing and thawing. -
Applications
Immunohistochemistry
Immunohistochemical staining of NTRK3 in rat dorsal horn (free floating cryostat section) using rabbit NTRK3 polyclonal antibody (Cat # PAB0735) at a dilution of 1 in 3000. Courtesy of Professor Xin Fu Zhou, The Flinders University of South Australia.Immunohistochemistry
IHC on rat trigeminal nerve (free floating cryo section) using rabbit NTRK3 polyclonal antibody (Cat # PAB0735) at a dilution of 1 : 1000. -
Gene Info — NTRK3
Entrez GeneID
4916Protein Accession#
Q16288Gene Name
NTRK3
Gene Alias
TRKC, gp145(trkC)
Gene Description
neurotrophic tyrosine kinase, receptor, type 3
Omim ID
191316Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers. [provided by RefSeq
Other Designations
ETS related protein-neurotrophic receptor tyrosine kinase fusion protein|ETV6-NTRK3 fusion|NT-3 growth factor receptor|OTTHUMP00000192915|neurotrophin 3 receptor|tyrosine kinase receptor C
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