IHC on rat trigeminal nerve (free floating cryo section) using rabbit NTRK3 polyclonal antibody (Cat # PAB0735) at a dilution of 1 : 1000.
Immunohistochemical staining of NTRK3 in rat dorsal horn (free floating cryostat section) using rabbit NTRK3 polyclonal antibody (Cat # PAB0735) at a dilution of 1 in 3000. Courtesy of Professor Xin Fu Zhou, The Flinders University of South Australia.
This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers. [provided by RefSeq
ETS related protein-neurotrophic receptor tyrosine kinase fusion protein,ETV6-NTRK3 fusion,NT-3 growth factor receptor,OTTHUMP00000192915,neurotrophin 3 receptor,tyrosine kinase receptor C