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Last updated: 2017/8/20
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SORT1 polyclonal antibody

  • Catalog # : PAB0734
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against partial recombinant SORT1.
  • Immunogen:
  • Recombinant protein corresponding to extracellular region of human SORT1.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Mouse, Rat
  • Form:
  • Lyophilized
  • Recommend Usage:
  • Immunohistochemistry (1:1000)
    ELISA (1:5000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • Lyophilized from PBS
  • Storage Instruction:
  • Store at 4°C on dry atmosphere.
    After reconstitution with deionized water, store at -20°C or lower.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Immunohistochemistry (Frozen sections)
  • Immunohistochemistry (Frozen sections)
  • IHC on rat spinal cord (free floating cryo section) using rabbit SORT1 polyclonal antibody (Cat # PAB0734) at a dilution of 1 : 1000.
  • Immunohistochemistry (Frozen sections)
  • Immunohistochemistry (Frozen sections)
  • IHC on rat DRG (free floating cryo section) using rabbit SORT1 polyclonal antibody (Cat # PAB0734) at a dilution of 1 : 1000.
  • Immunohistochemistry (Frozen sections)
  • Immunohistochemistry (Frozen sections)
  • IHC on rat trigeminal nerve (free floating cryo section) using rabbit SORT1 polyclonal antibody (Cat # PAB0734) at a dilution of 1 : 1000.
  • ELISA
  • Application Image
  • Immunohistochemistry (Frozen sections)
  • Immunohistochemistry (Frozen sections)
  • enlarge
  • Immunohistochemistry (Frozen sections)
  • Immunohistochemistry (Frozen sections)
  • enlarge
  • Immunohistochemistry (Frozen sections)
  • Immunohistochemistry (Frozen sections)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 6272
  • Gene Name:
  • SORT1
  • Gene Alias:
  • Gp95,NT3
  • Gene Description:
  • sortilin 1
  • Gene Summary:
  • This gene encodes a protein that is a multi-ligand type-1 receptor with similarity to the yeast carboxypeptidase Y sorting receptor Vps10 protein. The encoded protein, a trans-Golgi network (TGN) transmembrane protein, binds a number of unrelated ligands that participate in a wide range of cellular processes; however, it lacks the typical features of a signalling receptor. In the TGN, furin mediates the activation of the mature binding form. The encoded protein consists of a large luminal domain, a single transmembrane segment and short C-terminal cytoplasmic tail. The luminal domain contains a cysteine-rich region similar to two corresponding segments in the yeast Vps10p; the cytoplasmic tail is similar to the corresponding segment of the cation-independent mannose 6-phosphate receptor and the tail also interacts with the VHS domains of GGA (Golgi-associated, gamma-adaptin homologous, ARF-interacting) proteins. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000013784,neurotensin receptor 3
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