TH polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of TH.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to amino acids 61-77 of human TH.
Sequence
SPRFIGRRQSLIEDARK
Host
Rabbit
Reactivity
Human, Rat
Form
Lyophilized
Recommend Usage
Immunohistochemistry (1:2000-1:5000)
The optimal working dilution should be determined by the end user.Storage Buffer
Lyophilized from PBS
Storage Instruction
Store at 4°C on dry atmosphere.
After reconstitution with deionized water, store at -20°C or lower.
Aliquot to avoid repeated freezing and thawing. -
Applications
Immunohistochemistry
Immunohistochemical staining of catecholaminergic neurons in the rat brain stem. -
Gene Info — TH
Entrez GeneID
7054Protein Accession#
P07101;P04177Gene Name
TH
Gene Alias
TYH
Gene Description
tyrosine hydroxylase
Omim ID
191290Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000011225|OTTHUMP00000011226|tyrosine 3-monooxygenase
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Interactome
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Disease
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