RFXAP polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against full length recombinantt RFXAP.
Immunogen
Recombinant protein corresponding to full length human RFXAP.
Host
Rabbit
Reactivity
Human
Form
Liquid
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In PBS (0.05% sodium azide)
Storage Instruction
Store at -20°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
ChIP
ChIP results obtained with the RFXAP polyclonal antibody (Cat # PAB0661). ChIP assays were performed using NALM cells (a cell line derived from human pre-B leukemia). -
Gene Info — RFXAP
Entrez GeneID
5994Gene Name
RFXAP
Gene Alias
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Gene Description
regulatory factor X-associated protein
Gene Ontology
HyperlinkGene Summary
Major histocompatibility (MHC) class II molecules are transmembrane proteins that have a central role in development and control of the immune system. The protein encoded by this gene, along with regulatory factor X-associated ankyrin-containing protein and regulatory factor-5, forms a complex that binds to the X box motif of certain MHC class II gene promoters and activates their transcription. Once bound to the promoter, this complex associates with the non-DNA-binding factor MHC class II transactivator, which controls the cell type specificity and inducibility of MHC class II gene expression. Mutations in this gene have been linked to bare lymphocyte syndrome type II, complementation group D. Transcript variants utilizing different polyA signals have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000018260|RFX DNA-binding complex 36 kDa subunit|RFX-associated protein
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Interactome
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Pathway
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