NR4A1 (phospho S351) polyclonal antibody
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Dot Blot (Peptide)
Dot blot analysis of NR4A1 (phospho S351) polyclonal antibody (Cat # PAB0547) on nitrocellulose membrane. 50 ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. P-Pab : phospho-antibody; P-Peptide : phospho-peptide; NP-Peptide : non-phospho-peptide.
-
Specification
Product Description
Rabbit polyclonal antibody raised against synthetic phosphopeptide of NR4A1.
Immunogen
Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S351 of human NR4A1.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Protein A purification
Recommend Usage
Dot Blot (1:100-500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Dot Blot (Peptide)
Dot blot analysis of NR4A1 (phospho S351) polyclonal antibody (Cat # PAB0547) on nitrocellulose membrane. 50 ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. P-Pab : phospho-antibody; P-Peptide : phospho-peptide; NP-Peptide : non-phospho-peptide. -
Gene Info — NR4A1
Entrez GeneID
3164Protein Accession#
NP_002126;P22736Gene Name
NR4A1
Gene Alias
GFRP1, HMR, MGC9485, N10, NAK-1, NGFIB, NP10, NUR77, TR3
Gene Description
nuclear receptor subfamily 4, group A, member 1
Omim ID
139139Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. The encoded protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq
Other Designations
TR3 orphan receptor|early response protein NAK1|growth factor-inducible nuclear protein N10|hormone receptor|orphan nuclear receptor HMR|steroid receptor TR3
-
Interactome
-
Pathway
-
Disease
-
Publication Reference
-
Insulin promotes hepatocarcinoma tumorigenesis by up-regulating PKM2 expression.
Jingjing Liu, Qiang Zhi, Yunpeng Liu, Ying Wang, Linlin Chen, Yuhao Ke, Lingsu Zeng, Xiaoling Wu, Xiaoning Yang, Bayasi Guleng, Hao Liu, Jianlin Ren.
Experimental Cell Research 2021 Nov; 408(2):112872.
Application：WB, Human, HepG2 cells.
-
Differential regulation of Nr4a subfamily nuclear receptors following mast cell activation.
Lundequist A, Calounova G, Wensman H, Ronnberg E, Pejler G.
Molecular Immunology 2011 Sep; 48(15-16):1753.
Application：WB-Ce, Human, Mouse, Human mast cells, Mouse bone marrow-derived Mast cells.
-
Nur-related factor 1 and nerve growth factor-induced clone B in human adrenal cortex and its disorders.
Lu L, Suzuki T, Yoshikawa Y, Murakami O, Miki Y, Moriya T, Bassett MH, Rainey WE, Hayashi Y, Sasano H.
The Journal of Clinical Endocrinology and Metabolism 2004 Aug; 89(8):4113.
-
Conversion of Bcl-2 from protector to killer by interaction with nuclear orphan receptor Nur77/TR3.
Lin B, Kolluri SK, Lin F, Liu W, Han YH, Cao X, Dawson MI, Reed JC, Zhang XK.
Cell 2004 Feb; 116(4):527.
-
Alternative, nonapoptotic programmed cell death: mediation by arrestin 2, ERK2, and Nur77.
Castro-Obregon S, Rao RV, del Rio G, Chen SF, Poksay KS, Rabizadeh S, Vesce S, Zhang XK, Swanson RA, Bredesen DE.
The Journal of Biological Chemistry 2004 Feb; 279(17):17543.
-
Insulin promotes hepatocarcinoma tumorigenesis by up-regulating PKM2 expression.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com