NR4A1 polyclonal antibody
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of NR4A1 in 15 ugs of NIH/3T3 cell lysate. Using NR4A1 polyclonal antibody (Cat # PAB0352) at 1 : 500 dilution.
-
Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of NR4A1.
Immunogen
A synthetic peptide corresponding to amino acids 251-266 of human NR4A1.
Host
Rabbit
Reactivity
Human, Mouse
Form
Liquid
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In buffer containing 0.05% sodium azide, 0.2% gelatin
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Western Blot (Cell lysate)
Western blot analysis of NR4A1 in 15 ugs of NIH/3T3 cell lysate. Using NR4A1 polyclonal antibody (Cat # PAB0352) at 1 : 500 dilution.Immunocytochemistry
Immunofluorescence
-
Gene Info — NR4A1
Entrez GeneID
3164Gene Name
NR4A1
Gene Alias
GFRP1, HMR, MGC9485, N10, NAK-1, NGFIB, NP10, NUR77, TR3
Gene Description
nuclear receptor subfamily 4, group A, member 1
Omim ID
139139Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. The encoded protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq
Other Designations
TR3 orphan receptor|early response protein NAK1|growth factor-inducible nuclear protein N10|hormone receptor|orphan nuclear receptor HMR|steroid receptor TR3
-
Interactome
-
Pathway
-
Disease
-
Publication Reference
-
Insulin promotes hepatocarcinoma tumorigenesis by up-regulating PKM2 expression.
Jingjing Liu, Qiang Zhi, Yunpeng Liu, Ying Wang, Linlin Chen, Yuhao Ke, Lingsu Zeng, Xiaoling Wu, Xiaoning Yang, Bayasi Guleng, Hao Liu, Jianlin Ren.
Experimental Cell Research 2021 Nov; 408(2):112872.
Application：WB, Human, HepG2 cells.
-
Activation of Nur77 by selected 1,1-Bis(3'-indolyl)-1-(p-substituted phenyl)methanes induces apoptosis through nuclear pathways.
Chintharlapalli S, Burghardt R, Papineni S, Ramaiah S, Yoon K, Safe S.
The Journal of Biological Chemistry 2005 May; 280(26):24903.
-
Insulin promotes hepatocarcinoma tumorigenesis by up-regulating PKM2 expression.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com