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Last updated: 2016/12/4
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AIFM1 polyclonal antibody

  • Catalog # : PAB0324
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of AIFM1.
  • Immunogen:
  • A synthetic peptide corresponding to amino acids 151-169 of human AIFM1.
  • Sequence:
  • RARDPGARVLIVSEDPELP
  • Host:
  • Rabbit
  • Reactivity:
  • Bovine, Dog, Human, Mouse, Rat
  • Form:
  • Liquid
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In serum (0.05% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • Western blot analysis of AIFM1 in human colon. Using AIFM1 polyclonal antibody (Cat # PAB0324) at 1 : 2000. Lane 1, normal colon. Lanes 2-7, colon carcinoma tissue lysates from 6 different patients. mAIF, thought to represent mitochondrial AIF.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining of AIFM1 in formalin-fixed, paraffin-embedded normal human colon. Using AIFM1 polyclonal antibody (Cat # PAB0324) at 1 : 2000. Hematoxylin-eosin counterstain. In this example, AIFM1 expression is predominant in the upper part of the crypt.
  • Immunohistochemistry (Frozen sections)
  • Immunoprecipitation
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Immunohistochemistry (Frozen sections)
  • Immunoprecipitation
  • Gene Information
  • Entrez GeneID:
  • 9131
  • Gene Name:
  • AIFM1
  • Gene Alias:
  • AIF,MGC111425,PDCD8
  • Gene Description:
  • apoptosis-inducing factor, mitochondrion-associated, 1
  • Gene Summary:
  • This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells that is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it effects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Several alternative transcripts encoding different isoforms have been identified for this gene. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000024007,OTTHUMP00000024008,OTTHUMP00000024009,programmed cell death 8,programmed cell death 8 (apoptosis-inducing factor),striatal apoptosis-inducing factor
  • Gene Pathway
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