TRHR polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant TRHR.
Immunogen
Recombinant protein corresponding to amino acids 350-400 of human TRHR.
Host
Rabbit
Reactivity
Chimpanzee, Dog, Human, Monkey
Form
Liquid
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In PBS (0.2% gelatin, 0.05% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of human TRHR in human brain lysate in the 1) absence and 2) presence of immunizing peptide. Using TRHR polyclonal antibody (Cat # PAB0315) at 0.5 ug/mL .Immunohistochemistry
IHC analysis of human thyroid using TRHR polyclonal antibody (Cat # PAB0315) at 10 ug/mL . -
Gene Info — TRHR
Entrez GeneID
7201Protein Accession#
NP_003292.1Gene Name
TRHR
Gene Alias
MGC141920
Gene Description
thyrotropin-releasing hormone receptor
Omim ID
188545Gene Ontology
HyperlinkGene Summary
Thyrotropin-releasing hormone (TRH; MIM 275120), a small neuropeptide, is widely distributed throughout the central and peripheral nervous system as well as in extraneural tissues. The peptide is synthesized in the hypothalamus and transported by the portal vascular system to the anterior pituitary where it acts on thyrotropic and lactotropic cells to promote secretion of TSH and prolactin, respectively. Thyrotropin-releasing hormone receptor is a G protein-coupled receptor that activates the inositol phospholipid-calcium-protein kinase C transduction pathway upon the binding of TRH. The TRHR gene is expressed in the thyrotrope cells of the anterior pituitary.[supplied by OMIM
Other Designations
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