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Last updated: 2016/10/23
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C12orf5 polyclonal antibody

  • Catalog # : PAB0309
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against partial recombinant C12orf5.
  • Immunogen:
  • Recombinant protein corresponding to amino acids 220-270 of human C12orf5.
  • Host:
  • Rabbit
  • Reactivity:
  • Chimpanzee, Dog, Human, Monkey
  • Form:
  • Liquid
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.2% gelatin, 0.05% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of human C12orf5 in MCF-7 cell lysate in the 1) absence and 2) presence of immunizing peptide using C12orf5 polyclonal antibody (Cat # PAB0309) at 2 ug/mL .
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Gene Information
  • Gene Name:
  • C12orf5
  • Gene Alias:
  • Gene Description:
  • chromosome 12 open reading frame 5
  • Gene Summary:
  • This gene is regulated as part of the p53 tumor suppressor pathway and encodes a protein with sequence similarity to the bisphosphate domain of the glycolytic enzyme that degrades fructose-2,6-bisphosphate. The protein functions by blocking glycolysis and directing the pathway into the pentose phosphate shunt. Expression of this protein also protects cells from DNA damaging reactive oxygen species and provides some protection from DNA damage-induced apoptosis. The 12p13.32 region that includes this gene is paralogous to the 11q13.3 region. [provided by RefSeq
  • Other Designations:
  • TP53-induced glycolysis and apoptosis regulator,transactivated by NS3TP2 protein
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