MAP3K7IP3 polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
Western blot analysis of MAP3K7IP3 in human kidney lysate in the 1) absence and 2) presence of immunizing peptide. Using MAP3K7IP3 polyclonal antibody (Cat # PAB0304) at 0.5 ug/mL .
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant MAP3K7IP3.
Immunogen
Recombinant protein corresponding to amino acids 50-100 of human MAP3K7IP3.
Host
Rabbit
Reactivity
Dog, Human, Mouse
Form
Liquid
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In PBS (0.2% gelatin, 0.05% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of MAP3K7IP3 in human kidney lysate in the 1) absence and 2) presence of immunizing peptide. Using MAP3K7IP3 polyclonal antibody (Cat # PAB0304) at 0.5 ug/mL . -
Gene Info — MAP3K7IP3
Entrez GeneID
257397Protein Accession#
AAQ88279Gene Name
MAP3K7IP3
Gene Alias
MGC45404, NAP1, TAB3
Gene Description
mitogen-activated protein kinase kinase kinase 7 interacting protein 3
Omim ID
300480Gene Ontology
HyperlinkGene Summary
The product of this gene functions in the NF-kappaB signal transduction pathway. The encoded protein, and the similar and functionally redundant protein MAP3K7IP2/TAB2, forms a ternary complex with the protein kinase MAP3K7/TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1. Subsequent MAP3K7/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor. The human genome contains a related pseudogene. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq
Other Designations
Mitogen-activated protein kinase kinase kinase 7-interacting protein 3|NF-kappa-B-activating protein 1|NFkB activating protein 1|OTTHUMP00000023112|TAK1 binding protein 3|TAK1-binding protein 3
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Interactome
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