IPO8 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant IPO8.
Immunogen
Recombinant protein corresponding to amino acids 850-900 of human IPO8.
Host
Rabbit
Reactivity
Chimpanzee, Human, Monkey
Form
Liquid
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In PBS (0.2% gelatin, 0.05% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of human IPO8 in HeLa cell lysate in the 1) absence and 2) presence of immunizing peptide. Using IPO8 polyclonal antibody (Cat # PAB0302) at 1 ug/mL .Immunocytochemistry
ICC staining of HeLa cells using IPO8 polyclonal antibody (Cat # PAB0302) at 5 ug/mL . -
Gene Info — IPO8
Entrez GeneID
10526Protein Accession#
NP_006381Gene Name
IPO8
Gene Alias
FLJ26580, RANBP8
Gene Description
importin 8
Omim ID
605600Gene Ontology
HyperlinkGene Summary
The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene is a member of a class of approximately 20 potential Ran targets that share a sequence motif related to the Ran-binding site of importin-beta. This protein binds to the nuclear pore complex and, along with RanGTP and RANBP1, inhibits the GAP stimulation of the Ran GTPase. [provided by RefSeq
Other Designations
RAN binding protein 8
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